Maternal Anemia and Pregnancy outcomes: a Systematic Review and Meta-Analysis

Authors

  • Ali Delpisheh Professor of Epidemiology, Public Health Faculty, Ilam University of Medical Sciences, Ilam, Iran.
  • Koroush Sayehmiri Associate Professor of Biostatistics, Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, Iran.
  • Naser Parizad Ph.D Candidate in Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Shoboo Rahmati MSc Student of Epidemiology, Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran.
Abstract:

Background  The aim of this study was to determine the relationship between maternal anemia during pregnancy and pregnancy outcomes. Materials and Methods  This systematic review was conducted in domestic (Sid, Iran.doc, Iran medex and Magiran) and international (PubMed, Science Direct, Cochrane, Medline, Web of Science, Scopus, Springer, Embase, Google scholar) databases from January 1, 1990 to April 10, 2016 with using standard key words "Pregnancy", "Pregnant women", "Hemoglobin/ haemoglobin", "Anemia/ anaemia", and "Pregnancy outcome". Relative risks (RR) and confidence intervals were extracted from each study. Results  Overall 30 studies with a total sample size of 1,194,746 were entered into the final meta-analysis. Maternal anemia in the first trimester showed a significant relationship with low birth weight (RR: 1.28, 95% CI, 1.10 - 1.50, P0.05) and pre-term birth (RR: 1.55, 95% CI, 0.83 - 2.88, P>0.05). Conclusion Maternal anemia during pregnancy in the first trimester in particular can be considered as a risk factor for pregnancy outcomes and must be treated as an advance.

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Journal title

volume 4  issue 8

pages  3323- 3342

publication date 2016-08-01

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